| Museum | Location | County |
|---|
| 1881 Courthouse Museum | Custer | Custer |
| Adams Homestead and Nature Preserve | McCook Lake | Union |
| Adams Museum & House | Deadwood | Lawrence |
| Akta Lakota Museum | Chamberlain | Brule |
| Armed Forces Military Display and Gifts | Wasta | Pennington |
| Augustana College Art Galleries | Sioux Falls | Minnehaha |
| Aurora County Museum | Plankinton | Aurora |
| Austin-Whittemore House | Vermillion | Clay |
| Badlands National Park | Interior | Jackson |
| Badlands Petrified Garden | Kadoka | Jackson |
| Beauvais Heritage Museum | Clark | Clark |
| Big Thunder Gold Mine | Keystone | Pennington |
| Black Hills Mining Museum | Lead | Lawrence |
| Black Hills Museum of Natural History | Hill City | Pennington |
| Bon Homme Heritage Museum | Tyndall | Bon Homme |
| Borglum Historical Center | Keystone | Pennington |
| Brookings County Museum | Volga | Brookings |
| Buechel Memorial Lakota Museum | St. Francis | Todd |
| Buffalo Historical Museum | Buffalo | Harding |
| Buffalo Interpretive Center | Fort Pierre | Stanley |
| Campbell Original Straw Bale Built Museum | Carthage | Miner |
| Carnegie Resource Center | Mitchell | Davison |
| Casey Tibbs South Dakota Rodeo Center | Fort Pierre | Stanley |
| Cecil & Phyllis Melcher Museum | Platte | Charles Mix |
| Celebrity Hotel Memorabilia Display | Deadwood | Lawrence |
| Center for Western Studies | Sioux Falls | Minnehaha |
| Chapel in the Hills | Rapid City | Pennington |
| Children's Museum of South Dakota | Brookings | Brookings |
| Civilian Conservation Corps Museum of South Dakota | Hill City | Pennington |
| Classic Wheels Museum | Clark | Clark |
| Codington County Heritage Museum | Watertown | Codington |
| Corn Palace | Mitchell | Davison |
| Corsica Historical Museum | Corsica | Douglas |
| Cramer Kenyon Heritage Home | Yankton | Yankton |
| Crazy Horse Memorial | Crazy Horse | Custer |
| Custer State Park | Custer | Custer |
| Dacotah Prairie Museum | Aberdeen | Brown |
| Dahl Arts Center | Rapid City | Pennington |
| Dakota Discovery Museum | Mitchell | Davison |
| Dakota Sunset Museum | Gettysburg | Potter |
| Dakota Territorial Museum | Yankton | Yankton |
| Dakotaland Museum | Huron | Beadle |
| Daneville Heritage Museum | Viborg | Turner |
| Day County Museum | Webster | Day |
| Days of '76 Museum | Deadwood | Lawrence |
| D.C. Booth Historic National Fish Hatchery | Spearfish | Lawrence |
| De Smet Depot Museum | De Smet | Kingsbury |
| Clear Lake Museum | Clear Lake | Deuel |
| Cheryl's Doll House | Lennox | Lincoln |
| Donald Christman Toy Museum | Lake Norden | Hamlin |
| Douglas County Museum | Armour | Douglas |
| Elkton Community Museum | Elkton | Brookings |
| Eureka Pioneer Museum | Eureka | McPherson |
| Faulk County Historical Museum | Faulkton | Faulk |
| Fort Meade Museum | Sturgis | Meade |
| Fort Sisseton Historical Park | Lake City | Marshall |
| Four Mile Old West Town | Custer | Custer |
| Frederick Area Historical Society | Frederick | Brown |
| Garretson Area Historical Society Museum | Garretson | Minnehaha |
| Geddes Historic Village | Geddes | Charles Mix |
| Granary Rural Cultural Center | Groton | Brown |
| Grand River Museum | Lemmon | Perkins |
| Grant County Historical Society Museum | Milbank | Grant |
| Great Plains Zoo & Delbridge Museum of Natural History | Sioux Falls | Minnehaha |
| Gregory County History Museum | Dallas | Gregory |
| Harry's Antique Safe Museum | Mitchell | Davison |
| Heritage Hall Museum | Freeman | Hutchinson |
| Heritage Center of Red Cloud Indian School | Pine Ridge Indian Reservation | Shannon |
| Hermosa Arts and History Museum | Hermosa | Custer |
| High Plains Western Heritage Center | Spearfish | Lawrence |
| Historic Adams House | Deadwood | Lawrence |
| Historic Chicago & Northwestern Railroad Depot | Redfield | Spink |
| Historic Prairie Village | Madison | Lake |
| Hollands Grist Mill | Milbank | Grant |
| Ingalls Homestead | De Smet | Kingsbury |
| International Vinegar Museum | Roslyn | Day |
| Jerauld County Pioneer Museum | Wessington Springs | Jerauld |
| J.W. Parmley Historical Home | Ipswich | Edmunds |
| Journey Museum and Gardens | Rapid City | Pennington |
| Keystone Historical Museum | Keystone | Pennington |
| Klein Museum | Mobridge | Walworth |
| Lake Norden Historical Society | Lake Norden | Hamlin |
| Lake Poinsett Visitor Center and Museum | Arlington | Brookings |
| Laura Ingalls Wilder Memorial Society | De Smet | Kingsbury |
| Lennox Museum | Lennox | Lincoln |
| Lewis and Clark Center Visitor Center | Yankton | Yankton |
| Little Village Farm Museum | Dell Rapids | Minnehaha |
| Loriks-Peterson Heritage House | Oldham | Kingsbury |
| Lyman County Museum | Presho | Lyman |
| Major James McLaughlin Heritage Center | McLaughlin | Corson |
| Mammoth Site of Hot Springs | Hot Springs | Fall River |
| McWhorter House Museum and Depot | Miller | Hand |
| Mellette House | Watertown | Codington |
| Midland Pioneer Museum | Midland | Haakon |
| Miner County Rural Life Museum | Howard | Miner |
| Minuteman Missile National Historic Site | Jackson County | Jackson |
| Mitchell Prehistoric Indian Village | Mitchell | Davison |
| Moody County Museum and Research Center | Flandreau | Moody |
| Mount Rushmore | Keystone | Pennington |
| Museum of Geology | Rapid City | Pennington |
| Museum of Visual Materials | Sioux Falls | Minnehaha |
| Museum of Wildlife, Science and Industry of NE South Dakota | Webster | Day |
| National Museum of Woodcarving | Custer | Custer |
| National Music Museum | Vermillion | Clay |
| National Presidential Wax Museum | Keystone | Pennington |
| Newell Museum | Newell | Butte |
| Nicollet Tower | Sisseton | Roberts |
| Oglala Lakota College Historical Center | Kyle | Shannon |
| Old Courthouse Museum | Sioux Falls | Minnehaha |
| Petrified Wood Park | Lemmon | Perkins |
| Pettigrew Home & Museum | Sioux Falls | Minnehaha |
| Pickler Mansion | Faulkton | Faulk |
| Pioneer Auto Show | Murdo | Jones |
| Pioneer Historical Museum of South Dakota | Hot Springs | Fall River |
| Pollock Visitor and Interpretive Center | Pollock | Campbell |
| Porter Sculpture Park | Montrose | McCook |
| Prairie Homestead | Philip | Haakon |
| Prayer Rock Museum | Britton | Marshall |
| Pyle House | Huron | Beadle |
| Redlin Art Center | Watertown | Codington |
| Scouter's Attic Museum | Sioux Falls | Minnehaha |
| Sioux Empire Medical Museum | Sioux Falls | Minnehaha |
| Smith Zimmermann Heritage Museum | Madison | Lake |
| South Dakota Air and Space Museum | Box Elder | Meade |
| South Dakota Amateur Baseball Hall of Fame | Lake Norden | Hamlin |
| South Dakota Art Museum | Brookings | Brookings |
| South Dakota Cultural Heritage Center | Pierre | Hughes |
| South Dakota Discovery Center | Pierre | Hughes |
| South Dakota Hall of Fame | Chamberlain | Brule |
| South Dakota National Guard Museum | Pierre | Hughes |
| South Dakota's Original 1880 Town | Murdo | Jones |
| South Dakota Agricultural Heritage Museum | Brookings | Brookings |
| South Dakota School of Mines & Technology APEX Gallery | Rapid City | Pennington |
| South Dakota State Capitol | Pierre | Hughes |
| South Dakota State Railroad Museum | Hill City | Pennington |
| South Dakota Tractor Museum | Kimball | Brule |
| Spink County Museum | Redfield | Spink |
| Springfield College Museum | Springfield | Bon Homme |
| Springfield Historical Society Museum | Springfield | Bon Homme |
| Stavig House | Sisseton | Roberts |
| Sturgis Motorcycle Museum & Hall of Fame | Sturgis | Meade |
| Telstar Mustang Shelby Cobra Restorations & Museum | Mitchell | Davison |
| Timber Lake and Area Museum | Timber Lake | Dewey |
| Trails, Trains & Pioneers Museum | Edgemont | Fall River |
| Tri-State Museum | Belle Fourche | Butte |
| Tripp County Historical Society Museum | Winner | Tripp |
| Union County Museum | Elk Point | Union |
| University of South Dakota Art Galleries | Vermillion | Clay |
| Vancura Park | Tabor | Bon Homme |
| Verendrye Museum | Fort Pierre | Stanley |
| Wade's Gold Mill | Hill City | Pennington |
| Washington Pavilion of Arts and Science | Sioux Falls | Minnehaha |
| W. H. Over Museum | Vermillion | Clay |
| Willow Lake Community Museum | Willow Lake | Clark |
| Wind Cave National Park | Hot Springs | Fall River |
| Wounded Knee Museum | Wall | Pennington |
